Nootropic in Focus: Caffeine Basics 101

by DeanMcKillop 4204 views Supplements

Nootropic in Focus: Caffeine Basics 101

Whether in the natural form found in coffee beans or synthetically found in items such as energy drinks, fat burners or pre workouts, all caffeine has the same stimulatory effect on the body no matter what its origin. Also commonly named 1, 3, 7-Trimethylxanthine, caffeine works by blocking the uptake of adenosine in the brain, which is responsible for sedation and relaxation, while also stimulating the adrenergic receptors causing a release of adrenaline and an increase in mental alertness. So contrary to popular belief, caffeine can actually be labelled as an anti sleep stimulant as well as an energy stimulant.

But can you have too much of a good thing?

Can we take too much or is it safe to use long term? As with all stimulatory ingredients, caffeine will in time have a reduced effect on the receptors allowing adenosine to become re-active even during the presence of caffeine, so dosage amount and frequency needs to be considered. In these cases, the noticeable awakening effect, increased heart rate and performance enhancement will subside despite using the same amount of caffeine and it is encouraged that caffeine consumption should then be reduced to re-sensitise its effect on the brain.

Traditionally speaking, sports supplementation products will range between 100mg and 300mg per serve, of which when compared to a single shot of coffee (80-100mg) has a profound effect on increasing mental alertness. As it stands now, the current recommendations for caffeine use per serve for a single bout of exercise when looking to increase performance is 3mg – 6mg of caffeine per kg of body weight.

For example, this would mean an 80kg individual may need to use between 240-480mg in a single dose to achieve performance enhancement.

Similarly, it is also advised to maintain a daily caffeine intake to approximately 500mg a day or lower, however the Australian average is close to 800mg a day.

What else does caffeine do?

What doesn’t caffeine do is probably a better question.

Here are some of the benefits listed from major (bold) to minor (italics).

Increase mental alertness – Increase anaerobic running capacity – Increase power output– Increase Aerobic Exercise – Reduce blood glucose disposal – Increase blood flow – Decrease fatigue – Increase fat oxidationDecrease visceral fat accumulation in a calorie surplus

All in all, caffeine is a pretty incredible ingredient and supplement to use. All adverse effects (increase in blood pressure, cortisol and heart rate) appear to be dose specific and highly individualised, whereby the length of use and receptor sensitivity appears to be the major contributing factors towards if these occur.

coffee beans

In saying that, it is critically important to recognise that any adverse effect must be considered in context, of which in the case of these 3 factors, a dose specific time point change will not have negative health effects.

One must look at their daily blood pressure, cortisol and heart rate as a reference for health, not at 1-2 hours within a 24hour time frame as the increase in these physiological markers are expected and do not give an indication of overall health.

To caffeine or not to caffeine, that is the question?

As with all supplements, inevitably the choice is up to the consumer. Caffeine will benefit the large majority of users and should be consumed at 3mg – 6mg of caffeine per kg of body weight, depending on the individual’s sensitivity and use of supplement history. As always, I recommend starting at the lower end of the spectrum to assess your tolerance first.

Caffeine can be used to enhance mental alertness, increase anaerobic output and to maximise power output but should be consumed with consideration to sleep, as its major role is to inhibit relaxation and sedation, so, for this reason, keep a performance level dose of caffeine at least 4-6 hours away from bedtime.

It may also be advised to periodically reduce or remove caffeine intake from time to time to maintain its effect, however, long term use and the need for cycling on and off caffeine is again highly individualised so choose the best protocol for you.

Caffeine is both naturally occurring and man made, but no matter what its origin is, caffeine has profound effects on performance and can even help improve lifestyle factors such as blood glucose control and enhancing lipolysis.

As with any stimulant based product, caution should always be used when deciding on dosage amounts so be mindful of the amount you are having in relation to your usage history, the desired performance enhancement you require and also how close to sleep it will be consumed. 


Exercise Scientist

I completed my Exercise Science Degree at the University of QLD and have worked in the fitness industry for over 8 years, including a short stint at the Brisbane Broncos in 2010 as a student. I also hold my Level 2 Strength and Conditioning Coach accreditation (ASCA) and have competed in 1 bodybuilding season, placing 2nd at the IFBB u85kg Nationals.

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